We address the question of whether it is possible to operate a time machine by manipulating matter and energy so as to manufacture closed timelike curves. This question has received a great deal of attention in the physics literature, with attempts to prove no- go theorems based on classical general relativity and various hybrid theories serving as steps along the way towards quantum gravity. Despite the effort put into these no-go theorems, there is no widely accepted definition of a time (...) machine. We explain the conundrum that must be faced in providing a satisfactory definition and propose a resolution. Roughly, we require that all extensions of the time machine region contain closed timelike curves; the actions of the time machine operator are then sufficiently "potent" to guarantee that closed timelike curves appear. We then review no-go theorems based on classical general relativity, semi-classical quantum gravity, quantum field theory on curved spacetime, and Euclidean quantum gravity. Our verdict on the question of our title is that no result of sufficient generality to underwrite a confident "yes" has been proven. Our review of the no-go results does, however, highlight several foundational problems at the intersection of general relativity and quantum physics that lend substance to the search for an answer. (shrink)

In this paper we look at the manual analysis of arguments and how this compares to the current state of automatic argument analysis. These considerations are used to develop a new approach combining a machine learning algorithm to extract propositions from text, with a topic model to determine argument structure. The results of this method are compared to a manual analysis.

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Replicating or exceeding human intelligence, not just in particular domains but in general, has always been a major goal of Artificial Intelligence (AI). We argue here that “human intelligence” is not only ill-defined, but often conflated with broader aspects of human psychology. Standard arguments for replicating it are morally unacceptable. We then suggest a reframing: that the proper goal of AI is not to replicate humans, but to complement them by creating diverse intelligences capable of collaborating with humans. This goal (...) renders issues of theory of mind, empathy, and caring, or community engagement, central to AI. It also challenges AI to better understand the circumstances in which human intelligence, including human moral intelligence, fails. (shrink)

The Planteome project provides a suite of reference and species-specific ontologies for plants and annotations to genes and phenotypes. Ontologies serve as common standards for semantic integration of a large and growing corpus of plant genomics, phenomics and genetics data. The reference ontologies include the Plant Ontology, Plant Trait Ontology, and the Plant Experimental Conditions Ontology developed by the Planteome project, along with the Gene Ontology, Chemical Entities of Biological Interest, Phenotype and Attribute Ontology, and others. The project also provides (...) access to species-specific Crop Ontologies developed by various plant breeding and research communities from around the world. We provide integrated data on plant traits, phenotypes, and gene function and expression from 95 plant taxa, annotated with reference ontology terms. (shrink)

Many philosophical theories of causation are egalitarian, rejecting a distinction between causes and mere causal conditions. We sought to determine the extent to which people's causal judgments discriminate, selecting as causes counternormal events—those that violate norms of some kind—while rejecting non-violators. We found significant selectivity of this sort. Moreover, priming that encouraged more egalitarian judgments had little effect on subjects. We also found that omissions are as likely as actions to be judged as causes, and that counternormative selectivity appears to (...) apply equally to actions and omissions. (shrink)

The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create (...) new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease. (shrink)

We show how faceted search using a combination of traditional classification systems and mixed-membership topic models can go beyond keyword search to inform resource discovery, hypothesis formulation, and argument extraction for interdisciplinary research. Our test domain is the history and philosophy of scientific work on animal mind and cognition. The methods can be generalized to other research areas and ultimately support a system for semi-automatic identification of argument structures. We provide a case study for the application of the methods to (...) the problem of identifying and extracting arguments about anthropomorphism during a critical period in the development of comparative psychology. We show how a combination of classification systems and mixed-membership models trained over large digital libraries can inform resource discovery in this domain. Through a novel approach of “drill-down” topic modeling—simultaneously reducing both the size of the corpus and the unit of analysis—we are able to reduce a large collection of fulltext volumes to a much smaller set of pages within six focal volumes containing arguments of interest to historians and philosophers of comparative psychology. The volumes identified in this way did not appear among the first ten results of the keyword search in the HathiTrust digital library and the pages bear the kind of “close reading” needed to generate original interpretations that is the heart of scholarly work in the humanities. Zooming back out, we provide a way to place the books onto a map of science originally constructed from very different data and for different purposes. The multilevel approach advances understanding of the intellectual and societal contexts in which writings are interpreted. (shrink)

John Shook’s Systematic Atheology, “composed mainly for the edification of atheism’s defenders,” (p. 37) is an attempt to understand and defend atheism in an organized way. The book is divided into three sections. The first is the attempt to define ‘atheist’, ‘atheology’, and their relationship by tracking historical uses of the terms. The second is an extensive history of atheistic and atheological western philosophers, and the third, which occupies the last half of the book, is the attempt to systematically (...) undermine every kind of argument for the existence of a god. In this review, I state the strengths and weaknesses of the book, summarize its main points, and provide reasons to think that the atheological project in the last half of the book fails. (shrink)

There is a recent and growing trend in philosophy that involves deferring to the claims of certain disciplines outside of philosophy, such as mathematics, the natural sciences, and linguistics. According to this trend— deferentialism , as we will call it—certain disciplines outside of philosophy make claims that have a decisive bearing on philosophical disputes, where those claims are more epistemically justified than any philosophical considerations just because those claims are made by those disciplines. Deferentialists believe that certain longstanding philosophical problems (...) can be swiftly and decisively dispatched by appeal to disciplines other than philosophy. In this paper we will argue that such an attitude of uncritical deference to any non-philosophical discipline is badly misguided. With reference to the work of John Burgess and David Lewis, we consider deference to mathematics. We show that deference to mathematics is implausible and that main arguments for it fail. With reference to the work of Michael Blome-Tillmann, we consider deference to linguistics. We show that his arguments appealing to deference to linguistics are unsuccessful. We then show that naturalism does not entail deferentialism and that naturalistic considerations even motivate some anti-deferentialist views. Finally, we set out deferentialism’s failings and present our own anti-deferentialist approach to philosophical inquiry. (shrink)

In its etymology and in popular discourse, the term ‘avant-garde’ is commonly associated with a future temporality, while in art-historical discourse, it represents a tradition of modernist innovation, periodised as ‘historical avant-garde’ and ‘neo-avant-garde’. Since this historical periodisation was first established in the 1950s, the avant-garde’s futurity has been repeatedly disputed, bringing the very notion of an avant-garde into question. This thesis takes as its starting point the predicament of ‘an avant-garde after the avant-garde’ as a means to investigate the (...) philosophico-political implications of a historical temporality marked by ‘afterness’. Writing in critical dialogue with scholarship that has articulated the avant-garde as a notion of historical time, the thesis modifies the parameters of this scholarship by foregrounding the category of historicism, and by reformulating the avant-garde as a notion that both resists and inhabits historical periodisation. As a study at the disciplinary intersection of comparative literature and critical theory, 'Ahead of its Time' proceeds via close readings of selected theories of the avant-garde (German literary scholar Peter Bürger’s foundational Theory of the Avant-Garde in the 1970s; British art theorist John Roberts’ formulation of a ‘suspensive avant-garde’ in the twenty-first century; and the intellectual debates of the Italian circle Neoavanguardia in the 1960s), while also mobilising the critical resources available in the thought of Walter Benjamin. Through a non-linear, comparativist critical analysis that discusses these theories in, and as, a Benjaminian constellation, the thesis proposes the avant-garde as a relational, indexical category that is constitutively split between historical continuity and historical rupture. In this manner, 'Ahead of its Time' revisits the broader question of mediation between universality and particularity, and by recasting it in temporal terms, it advocates a chronopolitics of singularity, whereby the avant-garde’s split between continuity and rupture also reveals the ethically-necessary relationship between self-determination and contingency. (shrink)

Since G.A. Cohen’s influential criticism, John Rawls’s focus on the basic structure of society has fallen out of favor in moral and political philosophy. The most prominent defenses of this focus has argued from particular conceptions of justice or from a moral division of labor. In this dissertation, I instead argue for the Rawlsian focus from the ways in which social institutions establish new obligations, rights and powers. I argue that full evaluation of individual conduct requires that we evaluate (...) the practices within which an individual’s actions occur. Likewise, full evaluation of practices often requires evaluating the systems within which actions occur. I argue that we should treat the basic structure of society as a moral subject because the full evaluation of the various institutions that constitute the basic structure requires that we evaluate the basic structure as a whole. This argument shows the advantages of the Rawlsian approach even when we do not accept contractualism, constructivism or the two principles of justice. We need only accept the view that the major social institutions establish obligations, rights, and powers for individuals as members of society. (shrink)

In the first part of this paper, I will briefly introduce the concept of incongruity and its relation to humor and seriousness, connecting the ideas of Arthur Schopenhauer and the contemporary work of John Morreall. I will reveal some of the relations between Schopenhauer's notion of "seriousness" and the existentialists such as Jean Paul Sartre, Simone Be Beauvoir, and Lewis Gordon. In section II, I will consider the relationship between playfulness and incongruity, noting the role that enjoyment of incongruity (...) plays in creative, non-dogmatic thinking. In section III, I will critique Morreall's arguments against the efficacy of humor as a means of serious protest, analyzing the complex relationship between the ambiguous terms "seriousness" and "playfulness". In the final section, I contend that Morreall's conception of humor, with which I generally agree, fails to adequately address subversive humor. He is cognizant of the benefits of a humorous attitude and of the work of rebellious groups who use humor, but his insistence that the play mode of humor precludes emotional attachment and practical concern, renders his philosophical analysis of humor far less comprehensive than his title suggests. I will make the case, contra Morreall, and he is the most prominent of many humor theorists who make similar points, that some humor in play mode is non-existentially, non-gravely serious, and intends to do more than simply "delight" audiences; the subversive humorist, in particular, is attempting to disclose and transmit information in such a way as to create change in both attitudes and practical social interactions. (shrink)

Introduction to the special issue in Pragmatics & Cognition focused on creativity, cognition, and material culture. With contributions from Maurice Bloch, Chris Gosden, Tim Ingold, John Kirsh, Carl Knappett & Sander van der Leeuw, Lambros Malafouris, Frédéric Vallée-Tourangeau, Kevin Warwick, and Tom Wynn and Frederick L. Coolidge.

Diaristic, mixed notes on: John Ruskin's The Poetry of Architecture (1837) and Modern Painters (1885); Caravaggio, Victorian Aesthetes, G.K. Chesterton, and Tacita Dean; Jay Fellows' Ruskin’s Maze: Mastery and Madness in His Art (1981); Slavoj Žižek at Jack Tilton Gallery, New York, New York, USA, April 23, 2009, “Architectural Parallax: Spandrels and Other Phenomena of Class Struggle”; “Titian, Tintoretto, Veronese: Rivals in Renaissance Venice”, Museum of Fine Arts, Boston, Massachusetts, USA, March 15-August 16, 2009; Janet Harbord, Chris Marker: (...) La Jetée (2009); The Politics of the Envelope, Princeton Envelope Group (PEG), ARC504, Princeton School of Architecture, Princeton, New Jersey, USA, Friday, May 8, 2009; Rhode Island School of Design, Degree Project Reviews, Division of Architecture & Design, Providence, Rhode Island, USA, May 16, 2009; etc. (shrink)

A novel advantage of the use of machine learning (ML) systems in medicine is their potential to continue learning from new data after implementation in clinical practice. To date, considerations of the ethical questions raised by the design and use of adaptive machine learning systems in medicine have, for the most part, been confined to discussion of the so-called “update problem,” which concerns how regulators should approach systems whose performance and parameters continue to change even after they have received regulatory (...) approval. In this paper, we draw attention to a prior ethical question: whether the continuous learning that will occur in such systems after their initial deployment should be classified, and regulated, as medical research? We argue that there is a strong prima facie case that the use of continuous learning in medical ML systems should be categorized, and regulated, as research and that individuals whose treatment involves such systems should be treated as research subjects. (shrink)

In Tulving’s initial characterization, episodic memory was one of multiple memory systems. It was postulated, in pursuit of explanatory depth, as displaying proprietary operations, representations, and substrates such as to explain a range of cognitive, behavioural, and experiential phenomena. Yet the subsequent development of this research program has, paradoxically, introduced surprising doubts about the nature, and indeed existence, of episodic memory. On dominant versions of the ‘common system’ view, on which a single simulation system underlies both remembering and imagining, there (...) are no processes unique to memory to support robust generalizations with inductive potential. Eliminativism about episodic memory seems to follow from the claim that it has no dedicated neurocognitive system of its own. After identifying this under-noticed threat, we push back against modern eliminativists by surveying recent evidence that still indicates specialized mechanisms, computations, and representations that are distinctly mnemic in character. We argue that contemporary realists about episodic memory can retain lessons of the common system approach while resisting the further move to eliminativism. (shrink)

In an anonymous referee report written in 1945, Church suggested a sweeping argument against verificiationism, the thesis that every truth is knowable. The argument, which was published with due acknowledgement by Fitch almost two decades later, has generated significant attention as well as some interesting successor arguments. In this paper, we present the most important episodes in this intellectual history using the logic that Church himself favoured, and we give reasons for thinking that the arguments are less than decisive. However, (...) we present some new arguments against verificationism that we believe to be dialectically effective. (shrink)

This paper presents an argument that certain AI safety measures, rather than mitigating existential risk, may instead exacerbate it. Under certain key assumptions - the inevitability of AI failure, the expected correlation between an AI system's power at the point of failure and the severity of the resulting harm, and the tendency of safety measures to enable AI systems to become more powerful before failing - safety efforts have negative expected utility. The paper examines three response strategies: Optimism, Mitigation, and (...) Holism. Each faces challenges stemming from intrinsic features of the AI safety landscape that we term Bottlenecking, the Perfection Barrier, and Equilibrium Fluctuation. The surprising robustness of the argument forces a re-examination of core assumptions around AI safety and points to several avenues for further research. (shrink)

Teaching while managing instructional workload is causal to the teaching-learning process. The study determined the teachers' instructional workload management to the teachers' teaching efficacy. It was conducted in a community college in Tangub City, Misamis Occidental. The descriptive-correlational design was used in the study. There were 15 program heads and 361 students who served as the respondents selected through a stratified random sampling technique. The researcher-made Teachers' Instructional Workload Management and Teachers' Teaching Efficacy Questionnaires were used as research instruments. Mean, (...) Standard Deviation, and Pearson Product-Moment Correlation Coefficient were used as statistical tools to analyze the data gathered. Results revealed that the teachers were very good in their instructional workload management. The teachers' teaching efficacy was very high. Some aspects of the teachers' instructional workload management like the preparation of instructional materials influenced the teachers' administration of assessment tasks and classroom management. Their conduct of consultation also influenced the administration of assessment tasks. Moreover, their submission of academic reports influenced the administration of assessment tasks and school resource utilization. The workload management of teachers play a crucial role in shaping teachers' teaching efficacy. It is recommended for teachers to manage their workload proactively since it can impact their teaching efficacy. (shrink)

What is to be learned from the chaotic downfall of the Weimar Republic and the erosion of European liberal statehood in the interwar period vis-a-vis the ongoing European crisis? This book analyses and explains the recurrent emergence of crises in European societies. It asks how previous crises can inform our understanding of the present crisis. The particular perspective advanced is that these crises not only are economic and social crises, but must also be understood as crises of public power, order (...) and authority. In other words, it argues that substantial challenges to the functional and normative setup of democracy and the rule of law were central to the emergence and the unfolding of these crises. The book draws on and adds to the rich ’crises literature’ developed within the critical theory tradition to outline a conceptual framework for understanding what societal crises are. The central idea is that societal crises represent a discrepancy between the unfolding of social processes and the institutional frameworks that have been established to normatively stabilize such processes. The crises at issue emerged in periods characterized by strong social, economic and technological transformations as well as situations of political upheaval. As such, the crises represented moments where the existing functional and normative grid of society, as embodied in notions of public order and authority, were severely challenged and in many instances undermined. Seen in this perspective, the book reconstructs how crises unfolded, how they were experienced, and what kind of responses the specific crises in question provoked. -/- Table of Contents -/- Introduction: European Crises of Public Power: From Weimar until Today, Poul F. Kjaer & Niklas Olsen / Part I: Semantics, Notions and Narratives of Societal Crisis / 1. What Time Frame Makes Sense for Thinking About Crises?, David Runciman / 2. The Stakes of Crises, Janet Roitman / Part II: Weimar and the Interwar Period: Ideologies of Anti-Modernism and Liberalism / 3. The Crisis of Modernity – Modernity as Crisis: Towards a Typology of Crisis Discourses in Interwar East Central Europe and Beyond, Balázs Trencsényi / 4. European Legitimacy Crisis – Weimar and Today: Rational and Theocratic Authority in the Schmitt-Strauss Exchange, John P. McCormick / 5. Crisis and the Consumer: Reconstructions of Liberalism in Twentieth Century Political Thought , Niklas Olsen / Part III: The Causes of Crises: From Corporatism to Governance / 6. The Constitutionalization of Labour Law and the Crisis of National Democracy , Chris Thornhill / 7. The Crisis in Labour Law: From Weimar to Austerity Ruth Dukes / 8. From the Crisis of Corporatism to the Crisis of Governance, Poul F. Kjaer / Part IV: The Euro and the Crisis of Law and Democracy / 9. What is left of the European Economic Constitution II? From Pyrrhic Victory to Cannae Defeat Christian Joerges / 10. Reflections on Europe’s “Rule of Law Crisis”, Jan-Werner Müller. 11. Democracy under Siege: The Decay of Constitutionalisation and the Crisis of Public Law and Public Opinion, Hauke Brunkhorst/ Part V: The Consequences of Crises and the Future of Europe / 12. Crises and Extra-Legality: From Above and From Below, William E. Scheuermann / 13. “We could all go Down the Road of Lebanon” – Crisis Thinking on the Anti-Muslim Far Right, Mikkel Thorup / 14. Conclusions and Perspectives: The Re-Constitution of Europe, Poul F. Kjaer & Niklas Olsen Index . (shrink)

Pinillos’ Why We Doubt presents a powerful critique of such global skeptical assertions as “I don’t know I am not a brain-in-a-vat (biv)” by introducing a cognitive mechanism that is sensitive to error possibilities and a Bayesian rule of rationality that this mechanism is designed to approximate. This multifaceted argument offers a novel counter to global skepticism, contending that our basis for believing such premises is underminable. In this work, we engage with Pinillos’ adoption of Bayesianism, questioning whether the Bayesian (...) principle that he invokes truly does fail to generate the verdict that we don’t we aren’t biv s, contrary to what Pinillos asserts. Furthermore, we argue that Pinillos’ empirical argument is not empirical enough; we need a lot more empirical work if we are going to counter global skepticism and win over neutral bystanders. (shrink)

NUTRIÇÃO SOBRE A AZOOSPERMIA EM BOVINOS -/- -/- E. I. C. da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim Departamento de Zootecnia – UFRPE sede -/- AZOOSPERMIA EM BOVINOS -/- INTRODUÇÃO -/- A falta completa de esperma no ejaculado pode ser devido a uma falha no processo de espermatogênese ou relacionada a causas no transporte do esperma. Com relação ao transporte, o esperma pode ser impedido de ser ejaculado mediante bloqueios ou oclusões no sistema do ducto extragonadal, ou (...) por causa de uma disfunção ejaculatória. Nos cães, por exemplo, a possibilidade de oclusão ser a causa pode ser determinada por medições de fosfatase alcalina (ALP) no plasma seminal, já que a ALP se origina do epidídimo e seminífero epitélio tubular. Se a concentração de ALP no fluido seminal for superior a 5000 UI/l, a amostra ejaculada contém fluido desses tecidos e a oclusão pode ser descartada. -/- As causas testiculares da azoospermia incluem a falha da espermatogênese, que pode ser causada por uma série de fatores; estes incluem fatores hormonais, imunológicos, congênitos, tóxicos, patogênicos, traumáticos e nutricionais. Aqui, as supressões na região do AZF (que contém sub-regiões AZFa, AZFb e AZFc) no cromossoma Y desempenham um papel importante, representando 10-15% dos casos de azoo- e oligospermia. Na região AFZc, o gene DAZ, que é suprimido na azoospermia, é considerado importante no controle espermatogênico, uma vez que a sua eliminação é frequentemente detectada em homens e/ou animais inférteis. -/- A perda total da capacidade de formação de espermatozoides pelo epitélio testicular e, portanto, a ausência de espermatozoides viáveis ou não no volume ejaculado pelo animal é denominado como azoospermia (VARNER et al., 2000), um macho nessas condições deve ser imediatamente retirado dos processos produtivos e não é, de forma alguma, viável para fins reprodutivos. A origem da causa pode ter caráter nutricional, ou outras, sendo multifatoriais; em processos crônicos severos pode-se chegar à azoospermia reversível, que é diagnosticada e corrigida de forma oportuna. Entre os principais fatores de caráter nutricional temos: -/- 18.1 Nitratos (NO3-) e nitritos (NO2-) -/- Quando os ruminantes consomem uma alimentação com elevadas concentrações de nitratos (presente principalmente nas forrageiras) parte do nitrato não pode ser imediatamente convertido em nitrito e, por fim, em amoníaco (todas essas transformações acontecem no rúmen mediante a flora microbiana); isso faz com que nitrato e nitrito se acumulem no rúmen. A adição do nitrato no rúmen intensifica o problema. O envenenamento por nitrato ocorre quando o nível de nitrito presente no rúmen excede a capacidade do microbiota para convertê-lo em amoníaco. Quando isto acontece, o nitrato e o nitrito são absorvidos através da parede do rúmen e entram na circulação sanguínea. É o nitrito que causa a toxicidade. -/- Estudou-se o equilíbrio ácido-básico e sua relação com a reprodução e produção, postulando a hipótese de que esse equilíbrio afeta os mecanismos endócrinos e metabólicos, além dos reprodutivos. -/- 18.2 Relação energia:proteína -/- Quando a alimentação apresenta deficiências de energia aumenta-se a degradação das gorduras (provenientes do tecido adiposo), acompanhada pela redução da liberação de insulina (hipoinsulinemia) afetando-se a lipogênese, mobilizando-se mais gordura corporal do que se sintetiza. -/- Situações como a acidose ruminal (excesso de grão e deficiência em fibras) ou alcalose ruminal (excesso de ureia com baixa energia digerível) resultam em perturbações sobre a fertilidade; além disso, deficiências energéticas graves que levam à cetose causam estresse com a liberação de catecolaminas, ACTH e TSH que afetam a secreção de GnRH, afetando por fim, a espermiogênese. -/- -/- Uma diminuição de energia na alimentação gera hipoglicemia que, ao mesmo tempo, produz hipoinsulinemia incrementando assim a lipólise em tecidos, gerando como produtos as cetonas. -/- A hipoinsulinemia juntamente com a cetonemia e a geração de beta-endorfinas, por problemas na alimentação, reduzem notavelmente a síntese de GnRH. A GnRH reduz a liberação do LH e FSH. A diminuição da liberação do LH provoca azoospermia hipogonadotrópica com efeitos de estimulação hormonal anormais segundo a avaliação endócrina, bem como a obstrução testicular inexplicada. -/- Se houver um aumento significativo na liberação de FSH, a azoospermia hipogonadotrópica é refletida em diagnóstico como disfunção testicular. -/- 18.3 Minerais (Selênio Se) -/- Quando os níveis de Se na dieta são deficientes, ocorrem falhas na formação e maturação espermática. O Se mostra uma grande influência na fertilidade do macho afetando a qualidade do sêmen, o plasma seminal contém elevadas quantidades de GSH-Px, cuja função é proteger a membrana do espermatozoide do ataque peroxidativo; além disso, na cauda do gameta masculino há um selenopeptídeo que faz com que, em uma deficiência de Se, produza-se uma fratura no meio da cauda do espermatozoide. -/- O esperma dos animais com deficiência de Se apresentam pobre motilidade com características de desenvolvimento anormal na cauda do esperma. Demonstrou-se que a deficiência de Se, não somente precipita o problema em reprodutores, mas que o esperma deformado, foi menos efetivo na subsequente fertilização do ovócito ovulado (HAWKES et al., 2001), ou seja, animais que possuem deficiência desse mineral podem ter esperma inapropriado para a destinação de inseminação artificial ou mesmo a monta natural, uma vez que a taxa de concepção estará bastante baixa. -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- BARRENHO, Gonçalo José Pinheiro. Nutrição e fertilidade em bovinos de leite. 2016. Dissertação de Mestrado. Universidade de Évora. -/- BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. -/- BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. -/- CHENOWETH, Peter J.; LORTON, Steven (Ed.). Animal Andrology: Theories and Applications. Boston: Cabi, 2014. -/- -/- DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. -/- DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. -/- DIAS, Juliano Cesar et al. Alguns aspectos da interação nutrição-reprodução em bovinos: energia, proteína, minerais e vitaminas. PUBVET, v. 4, p. Art. 738-743, 2010. -/- FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. -/- FRENEAU, G. E.; GUIMARÃES, J. D. Curso Teórico-Prático de Andrologia Bovina. Goiânia: Laboratório de andrologia e Tecnologia de Sêmen da Escola de Veterinária da Universidade Federal de Goiás, 2000. -/- GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. -/- HAWKES, WAYNE CHRIS; TUREK, PAUL J. Effects of dietary selenium on sperm motility in healthy men. Journal of Andrology, v. 22, n. 5, p. 764-772, 2001. -/- MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. -/- SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. -/- THATCHER, W. W. et al. Strategies for improving fertility in the modern dairy cow. Theriogenology, v. 65, n. 1, p. 30-44, 2006. -/- TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. -/- VARNER, D. D. et al. Techniques for evaluating selected reproductive disorders of stallions. Animal reproduction science, v. 60, p. 493-509, 2000. (shrink)

Supervision of teachers is essential for ensuring effective educational practices, fostering professional development, and achieving student success. The study determined the relationship of program heads' supervisory practices to the teachers’ teaching efficacy. It was conducted in a community college in Tangub City, Misamis Occidental. The descriptive-correlational design was used in the study. There were 146 faculty and 361 students who served as the respondents selected through a stratified random sampling technique. The adapted Program Heads’ Supervisory Practices and researcher-made Teachers’ Teaching (...) Efficacy Questionnaires were used as research instruments. Mean, Standard Deviation, and Pearson Product-Moment Correlation Coefficient were used as statistical tools to analyze the data gathered. Results revealed that the program heads were good in their supervisory practices. The teachers’ teaching efficacy was very high. The program heads’ supervisory practices did not influence the teacher’s teaching efficacy. The strategies employed by program heads in their supervisory roles do not always translate into improved teaching efficiency. The study's findings indicate that program heads need to adopt more responsive and tailored supervisory practices that directly address the specific needs of teachers to enhance teaching efficacy. This may involve integrating targeted professional development focused on practical classroom strategies and fostering peer collaboration to share best practices. Program heads may prioritize open communication and continuous feedback mechanisms to better align their supervisory approaches with the realities of classroom instruction, ensuring that support translates into improved teaching efficiency. (shrink)

Moral encroachment is the thesis that morality has an effect---unrecognized by traditional epistemology---on which doxastic states are epistemically appropriate. The thesis is increasingly popular among those who, in opposition to Gendler (2011), desire harmony between epistemic and moral demands on belief. This paper has three main goals. First, drawing on attractive structural principles concerning belief and justification, it is shown that a thoroughgoing harmony between moral and epistemic demands is implausible. This weakens the motivation for positing moral encroachment, but a (...) proponent might still hope that moral encroachment can have a significant effect, so that many of the central cases of apparent disharmony can be avoided. The next goal of the paper is to argue that any significant effect of moral encroachment would manifest itself in the credences which are most epistemically appropriate. Finally, it is shown that even a small effect of moral encroachment on credence is in tension with widely accepted basic constraints on epistemically appropriate credence. (shrink)

The supervision of teachers is essential for ensuring effective teaching methods, ongoing professional growth, and student success. This study explored the experiences of program heads in supervising teachers. It was conducted in a local college in Tangub City, Misamis Occidental. The phenomenological design was used in the study. Eleven program heads served as the participants selected through the purposive sampling technique. The Interview Guide was used as the research instrument. Moustakas' transcendental phenomenology of data analysis was utilized to analyze the (...) data gathered. Results revealed the following main themes: the critical role of supervision in advancing teacher development and educational excellence, mutual learning and growth, the role of program heads in teacher supervision, overcoming challenges in teacher supervision, and effective communication strategies. Supervision improves teaching and learning quality, which supports professional development. The complex nature of supervisory roles requires adaptive strategies and strong support networks. It is recommended for program heads and teachers to establish open communication to help address the challenges encountered during supervision. (shrink)

Super-Humeans argue that the most parsimonious ontology of the natural world compatible with our best physical theories consists exclusively of particles and the distance relations between them. This paper argues by contrast that Super-Humean reduction goes insufficiently far, by showing there to be a more parsimonious ontology compatible with physics: Ultimate-Humeanism. This novel view posits an ontology consisting solely of the particles and distance relations required for the existence of a single brain. Super-Humeans impose conditions on what counts as an (...) ontology of the natural world to avoid their view slipping into this kind of ontology, but these conditions are arbitrarily imposed and once this is exposed, Super-Humeans face a dilemma. Either they can embrace Ultimate-Humeanism as the minimal ontology of the natural world compatible with physics, or (more likely) they can rethink the methodology that got them there. Overall, this paper argues that Super-Humeanism currently lacks principled motivation, outlines a framework for naturalistic ontological reductions, and exposes the consequences of unchecked adherence to a simplicity-driven methodology. (shrink)

Human obsolescence is imminent. We are living through an era in which our activity is becoming less and less relevant to our well-being and to the fate of our planet. This trend toward increased obsolescence is likely to continue in the future, and we must do our best to prepare ourselves and our societies for this reality. Far from being a cause for despair, this is in fact an opportunity for optimism. Harnessed in the right way, the technology that hastens (...) our obsolescence can open us up to new utopian possibilities and enable heightened forms of human flourishing. (shrink)

This paper provides a principled and elegant solution to the Gettier problem. The key move is to draw a general metaphysical distinction and conscript it for epistemological purposes. Section 1 introduces the Gettier problem. Sections 2–5 discuss instructively wrong or incomplete previous proposals. Section 6 presents my solution and explains its virtues. Section 7 answers the most common objection.

This paper introduces a new, expanded range of relevant cognitive psychological research on collaborative recall and social memory to the philosophical debate on extended and distributed cognition. We start by examining the case for extended cognition based on the complementarity of inner and outer resources, by which neural, bodily, social, and environmental resources with disparate but complementary properties are integrated into hybrid cognitive systems, transforming or augmenting the nature of remembering or decision-making. Adams and Aizawa, noting this distinctive complementarity argument, (...) say that they agree with it completely: but they describe it as “a non-revolutionary approach” which leaves “the cognitive psychology of memory as the study of processes that take place, essentially without exception, within nervous systems.” In response, we carve out, on distinct conceptual and empirical grounds, a rich middle ground between internalist forms of cognitivism and radical anti-cognitivism. Drawing both on extended cognition literature and on Sterelny’s account of the “scaffolded mind” (this issue), we develop a multidimensional framework for understanding varying relations between agents and external resources, both technological and social. On this basis we argue that, independent of any more “revolutionary” metaphysical claims about the partial constitution of cognitive processes by external resources, a thesis of scaffolded or distributed cognition can substantially influence or transform explanatory practice in cognitive science. Critics also cite various empirical results as evidence against the idea that remembering can extend beyond skull and skin. We respond with a more principled, representative survey of the scientific psychology of memory, focussing in particular on robust recent empirical traditions for the study of collaborative recall and transactive social memory. We describe our own empirical research on socially distributed remembering, aimed at identifying conditions for mnemonic emergence in collaborative groups. Philosophical debates about extended, embedded, and distributed cognition can thus make richer, mutually beneficial contact with independently motivated research programs in the cognitive psychology of memory. (shrink)

Researchers recently demonstrated a strong direct relationship between judgments about what a person knows and judgments about how a person should act. But it remains unknown whether actionability judgments cause knowledge judgments, or knowledge judgments cause actionability judgments. This paper uses causal modeling to help answer this question. Across two experiments, we found evidence that actionability judgments cause knowledge judgments.

‘There is no place in the phenomenology of fully absorbed coping’, writes Hubert Dreyfus, ‘for mindfulness. In flow, as Sartre sees, there are only attractive and repulsive forces drawing appropriate activity out of an active body’1. Among the many ways in which history animates dynamical systems at a range of distinctive timescales, the phenomena of embodied human habit, skilful movement, and absorbed coping are among the most pervasive and mundane, and the most philosophically puzzling. In this essay we examine both (...) habitual and skilled movement, sketching the outlines of a multidimensional framework within which the many differences across distinctive cases and domains might be fruitfully understood. Both the range of movement phenomena which can plausibly be seen as instances of habit or skill, and the space of possible theories of such phenomena are richer and more disparate than philosophy easily encompasses. We seek to bring phenomenology into contact with relevant movements in psychological theories of skilful action, in the belief that phenomenological philosophy and cognitive science can be allies rather than antagonists. (shrink)

Friendship is an important part of the good life. While many roboticists are eager to create friend-like robots, many philosophers and ethicists are concerned. They argue that robots cannot really be our friends. Robots can only fake the emotional and behavioural cues we associate with friendship. Consequently, we should resist the drive to create robot friends. In this article, I argue that the philosophical critics are wrong. Using the classic virtue-ideal of friendship, I argue that robots can plausibly be considered (...) our virtue friends - that to do so is philosophically reasonable. Furthermore, I argue that even if you do not think that robots can be our virtue friends, they can fulfil other important friendship roles, and can complement and enhance the virtue friendships between human beings. (shrink)

In a single-iteration fake barn case, the agent correctly identifies an object of interest on the first try, despite the presence of nearby lookalikes that could have mislead her. In a multiple-iteration fake barn case, the agent first encounters several fakes, misidentifies each of them, and then encounters and correctly identifies a genuine item of interest. Prior work has established that people tend to attribute knowledge in single-iteration fake barn cases, but multiple-iteration cases have not been tested. However, some theorists (...) contend that multiple-iteration cases are more important and will elicit a strong tendency to deny knowledge. Here I report a behavioural experiment investigating knowledge judgments in multiple-iteration fake barn cases. The main finding is that people tend to attribute knowledge in these cases too. Ironically, the results indicate that the presence of fakes could prevent iterated errors from lowering knowledge attributions. The results also provide evidence that ordinary knowledge attributions are based on attributions of cognitive ability. (shrink)

This article argues that access to meaningful sexual experience should be included within the set of the goods that are subject to principles of distributive justice. It argues that some people are currently unjustly excluded from meaningful sexual experience and it is not implausible to suggest that they might thereby have certain claim rights to sexual inclusion. This does not entail that anyone has a right to sex with another person, but it does entail that duties may be imposed on (...) society to foster greater sexual inclusion. This is a controversial thesis and this article addresses this controversy by engaging with four major objections to it: the misogyny objection; the impossibility objection; the stigmatisation objection; and the unjust social engineering objection. (shrink)

What is an occurrent mental state? According to a common scholastic answer such a state is at least in part a quality of the mind. When I newly think about a machiatto, say, my mind acquires a new quality. However, according to a view discussed by John Buridan (who rejects it) and John of Mirecourt (who is condemned in 1347 for considering it “plausible”), an occurrent mental state is not even in part a quality. After sketching some of (...) the history of this position, I will present two common arguments against it—the argument from change and the argument from agency. I will then turn to Mirecourt’s own position on the matter. Mirecourt, I show, in fact offers us two different theories about occurrent mental states. The first, which I call the conservation theory, accepts that mental states are in part qualities. However, a mental state is a quality together with an action on the side of the mind, namely, its conservation of a quality within itself. The second position, which I will call the pure-action theory, holds that an occurrent mental state is not even in part a quality; instead, it is an action the mind performs which is neither the production nor the conservation of a quality within itself. Mirecourt characterizes such pure actions as “modes” of the mind, and it is this position which is condemned in 1347. In the final section, I turn to an objection that both Buridan and Mirecourt raise against the pure-action theory: if accidental states of the mind are mere modes of the mind, then why not suppose that all accidents are mere modes of the subjects which they qualify? (shrink)

Computation and Metacognitive skills are essential sub-skills under the domain of Critical Thinking which is a 21 st Century Skill. Having acquired these skills can greatly help students to have a better performance in the Mathematics course. The purpose of this study was to determine whether computation and metacognitive skills are significant predictors of students' performance in Mathematics. Students from four sections of the course Mathematics in the Modern World which was offered during the first semester of the academic year (...) 2018-2019 were selected as the participants of this study which was conducted at Gov. Alfonso D. Tan College, Tangub City, Misamis Occidental, Philippines. The results of this study showed that students' scores in computation and metacognitive test of skills significantly correlate with the students' performance in Mathematics in terms of Grade Point Average (GPA) and a positive direct relationship has been established. Using the Regression Analysis, the result revealed that both computation and metacognitive skills of the students were significant predictors of their performance in Mathematics. These research outcomes affirm that if students acquire these skills, they tend to perform better in Mathematics. This suggests that teachers are encouraged to be more strategic in training the students to acquire and develop computation and metacognitive skills by administering various mathematical problems that encourage students to think critically. (shrink)

Almost everyone believes that testimony can transmit knowledge from speaker to hearer. What some philosophers mean by this is ordinary and pedestrian-- they mean only that, in at least some cases, a speaker S knows that p, S testifies that p to a hearer H, and H comes to know that p as a result of believing S's testimony. There is disagreement about how this occurs, but that it does occur is sufficient for the transmission of knowledge in the intended (...) sense. On this understanding of transmission, the natural questions are these: (1) What conditions, in addition to speaker knowledge and speaker testimony, are sufficient for the hearer to gain testimonial knowledge?; and (2) Is speaker knowledge always necessary for testimonial knowledge? That is: Is all testimonial knowledge transmitted knowledge? (shrink)

The paper begins by reviewing two problems for fallibilism: the lottery problem, or the problem of explaining why fallible evidence, though otherwise excellent, is not enough to know that one will lose the lottery, and Gettier problems. It is then argued that both problems can be resolved if we note an important illocutionary force of knowledge attributions: namely, that when we attribute knowledge to someone we mean to give the person credit for getting things right. Alternatively, to say that a (...) person knows is to say that she got things right due to her own abilities, efforts and actions, rather than due to dumb luck, or blind chance, or something else. (shrink)

Many philosophers claim that interesting forms of epistemic evaluation are insensitive to truth in a very specific way. Suppose that two possible agents believe the same proposition based on the same evidence. Either both are justified or neither is; either both have good evidence for holding the belief or neither does. This does not change if, on this particular occasion, it turns out that only one of the two agents has a true belief. Epitomizing this line of thought are thought (...) experiments about radically deceived “brains in vats.” It is widely and uncritically assumed that such a brain is equally justified as its normally embodied human “twin.” This “parity” intuition is the heart of truth-insensitive theories of core epistemological properties such as justification and rationality. Rejecting the parity intuition is considered radical and revisionist. In this paper, I show that exactly the opposite is true. The parity intuition is idiosyncratic and widely rejected. A brain in a vat is not justified and has worse evidence than its normally embodied counterpart. On nearly every ordinary way of evaluating beliefs, a false belief is significantly inferior to a true belief. Of all the evaluations studied here, only blamelessness is truth-insensitive. (shrink)

I consider a serious objection to the knowledge account of assertion and develop a response. In the process I introduce important new data on prompting assertion, which all theorists working in the area should take note of.

This paper advances our understanding of the norms of assertion in two ways. First, I evaluate recent studies claiming to discredit an important earlier finding which supports the hypothesis that assertion has a factive norm. In particular, I evaluate whether it was due to stimuli mentioning that a speaker’s evidence was fallible. Second, I evaluate the hypothesis that assertion has a truth-insensitive standard of justification. In particular, I evaluate the claim that switching an assertion from true to false, while holding (...) all else objectively constant, is irrelevant to attributions of justification. Two pre-registered experiments provide decisive evidence against each claim. In the first experiment, switching from mentioning to not mentioning fallibility made no difference to assertability attributions, thereby disproving the criticism concerning fallibility. By contrast, switching an assertion from true to false decreased the rate of assertability attribution from over 90% to less than 20%, thereby replicating and vindicating the original finding supporting a factive norm. In the second experiment, switching an assertion from true to false decreased the rate of justification attribution from over 80 to 10%, thereby undermining the hypothesis that assertion’s standard of justification is truth-insensitive. The second experiment also demonstrates that perspective-taking influences attributions of justification, and it provides initial evidence that the standard of justification for assertion is stricter than the standard for belief. (shrink)

If the contents of our thoughts are partly determined by facts outside our heads, can we still know those contents directly, without investigating our environment? What if we were surreptitiously switched to Twin-Earth? Would we know the contents of our thoughts under these unusual circumstances? By looking carefully at what determines the content of a second-order thought, a candidate for self-knowledge, the paper argues that we can know the contents of our thoughts directly, even after being switched. Learning about the (...) switch, however, does raise some interesting difficulties. (shrink)

Compatibilism is the view that moral responsibility is compatible with determinism. Natural compatibilism is the view that in ordinary social cognition, people are compatibilists. Researchers have recently debated whether natural compatibilism is true. This paper presents six experiments (N = 909) that advance this debate. The results provide the best evidence to date for natural compatibilism, avoiding the main methodological problems faced by previous work supporting the view. In response to simple scenarios about familiar activities, people judged that agents had (...) moral responsibilities to perform actions that they were unable to perform (Experiment 1), were morally responsible for unavoidable outcomes (Experiment 2), were to blame for unavoidable outcomes (Experiments 3-4), deserved blame for unavoidable outcomes (Experiment 5), and should suffer consequences for unavoidable outcomes (Experiment 6). These findings advance our understanding of moral psychology and philosophical debates that depend partly on patterns in commonsense morality. (shrink)

In “Perceptual Confidence,” I argue that our perceptual experiences assign degrees of confidence. In “Precision, not Confidence, Describes the Uncertainty of Perceptual Experience,” Rachel Denison disagrees. In this reply I first clarify what i mean by ‘perceptual experiences’, ‘assign’ and ‘confidence’. I then argue, contra Denison, that perception involves automatic categorization, and that there is an intrinsic difference between a blurry perception of a sharp image and a sharp perception of a blurry image. -/- .

Recent work has shown that knowledge attributions affect how people think others should behave, more so than belief attributions do. This paper reports two experiments providing evidence that knowledge attributions also affect behavioral predictions more strongly than belief attributions do, and knowledge attributions facilitate faster behavioral predictions than belief attributions do. Thus, knowledge attributions play multiple critical roles in social cognition, guiding judgments about how people should and will behave.

This paper addresses the foundations of Teleological Individualism, the view that organisms, even non-sentient organisms, are goal-oriented systems while biological collectives, such as ecosystems or conspecific groups, are mere assemblages of organisms. Typical defenses of Teleological Individualism ground the teleological organization of organisms in the workings of natural selection. This paper shows that grounding teleological organization in natural selection is antithetical to Teleological Individualism because such views assume a view about the units of selection on which it is only individual (...) organisms that are units of selection. However, none of the Conventionalist, Reductionist, or Multi-Level Realist theories serve to justify such an assumption. Thus, Teleological Individualism cannot be grounded in natural selection. (shrink)